These images are from an 76 year
old man, who suffered a severe fall 6 months before seeking medical attention.
He complained of memory loss, and had been depressed since the death of his
wife. He had a history of alcoholism, with several hospital admissions for
gastrointestinal bleeding.
Note the large fluid collection
displacing the brain. It is white on T2-weighted images, and, of course,
non-perfused on SPECT. The lateral and third ventricles are a bit large, partly
due to the effects of age and partly to the effects of alcohol abuse. The
mammillary bodies are small in this case compared to the normal, a finding
commonly seen in alcoholics.